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Membrane bioreactors for hospital wastewater treatment: recent advancements in membranes and processes

《化学科学与工程前沿（英文）》 2022年 第16卷 第5期   页码 634-660 doi: 10.1007/s11705-021-2107-1

摘要： Discharged hospital wastewater contains various pathogenic microorganisms, antibiotic groups, toxic organic compounds, radioactive elements, and ionic pollutants. These contaminants harm the environment and human health causing the spread of disease. Thus, effective treatment of hospital wastewater is an urgent task for sustainable development. Membranes, with controllable porous and nonporous structures, have been rapidly developed for molecular separations. In particular, membrane bioreactor (MBR) technology demonstrated high removal efficiency toward organic compounds and low waste sludge production. To further enhance the separation efficiency and achieve material recovery from hospital waste streams, novel concepts of MBRs and their applications are rapidly evolved through hybridizing novel membranes (non hydrophilic ultrafiltration/microfiltration) into the MBR units (hybrid MBRs) or the MBR as a pretreatment step and integrating other membrane processes as subsequent secondary purification step (integrated MBR-membrane systems). However, there is a lack of reviews on the latest advancement in MBR technologies for hospital wastewater treatment, and analysis on its major challenges and future trends. This review started with an overview of main pollutants in common hospital wastewater, followed by an understanding on the key performance indicators/criteria in MBR membranes (i.e., solute selectivity) and processes (e.g., fouling). Then, an in-depth analysis was provided into the recent development of hybrid MBR and integrated MBR-membrane system concepts, and applications correlated with wastewater sources, with a particular focus on hospital wastewaters. It is anticipated that this review will shed light on the knowledge gaps in the field, highlighting the potential contribution of hybrid MBRs and integrated MBR-membrane systems toward global epidemic prevention.

关键词： membrane technology     membrane bioreactor     hospital wastewater     hybrid MBR     integrated MBR-membrane system    

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Removal efficiencies of natural and synthetic progesterones in hospital wastewater treated by different

《环境科学与工程前沿（英文）》 2022年 第16卷 第10期 doi: 10.1007/s11783-022-1558-z

摘要：

● The concentrations of 61 progesterones in HWW, PFTE, SBTE were evaluated.

关键词： Progesterones     Hospital wastewater     Primary filtration treatment effluent     Secondary biological treatment effluent     Disinfection process    

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Qualitative analysis of direction of public hospital reforms in China

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《医学前沿（英文）》 2018年 第12卷 第2期   页码 218-223 doi: 10.1007/s11684-017-0534-7

摘要：

Reforms in public hospitals are among the most important improvements in China’s health care system over the last two decades. However, the reforms that should be implemented in public hospitals are unclear. Thus, a feasible direction of reforms in Chinese public hospitals is suggested and reliable policy suggestions are provided for the government to reform public hospitals. The data used in this study were mainly derived from a qualitative study. Focus group discussions and in-depth interviews were conducted in Shanghai, Guangdong, and Gansu between May and December 2014. Government funding accounted for approximately eight percent of the total annual revenue of public hospitals in China, and the insufficient government subsidy considerably affects the operation mechanism of public hospitals. However, solely increasing this subsidy cannot address the inappropriate incentives of public hospitals in China. The most crucial step in setting the direction of reforms in public hospitals in China is transforming inappropriate incentives by implementing a new evaluation index system for directors and physicians in public hospitals.

关键词： public hospital     government hospital     public funding     operation mechanism    

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SinoSCORE: a logistically derived additive prediction model for post-coronary artery bypass grafting in-hospital

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《医学前沿（英文）》 2013年 第7卷 第4期   页码 477-485 doi: 10.1007/s11684-013-0284-0

摘要：

This study aims to construct a logistically derived additive score for predicting in-hospital mortality risk in Chinese patients undergoing coronary artery bypass surgery (CABG). Data from 9839 consecutive CABG patients in 43 Chinese centers were collected between 2007 and 2008 from the Chinese Coronary Artery Bypass Grafting Registry. This database was randomly divided into developmental and validation subsets (9:1). The data in the developmental dataset were used to develop the model using logistic regression. Calibration and discrimination characteristics were assessed using the validation dataset. Thresholds were defined for each model to distinguish different risk groups. After excluding 275 patients with incomplete information, the overall mortality rate of the remaining 9564 patients was 2.5%. The SinoSCORE model was constructed based on 11 variables: age, preoperative NYHA stage III or IV, chronic renal failure, extracardiac arteriopathy, chronic obstructive pulmonary disease, preoperative atrial fibrillation or flutter (within 2βweeks), left ventricular ejection fraction, other elective surgery, combined valve procedures, preoperative critical state, and BMI. In the developmental dataset, calibration using a Hosmer-Lemeshow (HL) test was at =β0.44 and discrimination based on the area under the receiver operating characteristic curve (ROC) was 0.80. In the validation dataset, the HL test was at =β0.34 and the area under the ROC (AUC) was 0.78. A logistically derived additive model for predicting in-hospital mortality among Chinese patients undergoing CABG was developed based on the most up-to-date multi-center data from China.

关键词： coronary artery bypass grafting     risk stratification     in-hospital mortality    

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Association between ICU quality and in-hospital mortality of V-V ECMO-supported patients—the ECMO quality

《医学前沿（英文）》 doi: 10.1007/s11684-023-1014-x

摘要： This cohort study was performed to explore the influence of intensive care unit (ICU) quality on in-hospital mortality of veno-venous (V-V) extracorporeal membrane oxygenation (ECMO)-supported patients in China. The study involved all V-V ECMO-supported patients in 318 of 1700 tertiary hospitals from 2017 to 2019, using data from the National Clinical Improvement System and China National Critical Care Quality Control Center. ICU quality was assessed by quality control indicators and capacity parameters. Among the 2563 V-V ECMO-supported patients in 318 hospitals, a significant correlation was found between ECMO-related complications and prognosis. The reintubation rate within 48 hours after extubation and the total ICU mortality rate were independent risk factors for higher in-hospital mortality of V-V ECMO-supported patients (cutoff: 1.5% and 7.0%; 95% confidence interval: 1.05–1.48 and 1.04–1.45; odds ratios: 1.25 and 1.23; P = 0.012 and P = 0.015, respectively). Meanwhile, the V-V ECMO center volume was a protective factor (cutoff of ≥ 50 cases within the 3-year study period; 95% confidence interval: 0.57–0.83, odds ratio: 0.69, P = 0.0001). The subgroup analysis of 864 patients in 11 high-volume centers further strengthened these findings. Thus, ICU quality may play an important role in improving the prognosis of V-V ECMO-supported patients.

关键词： veno-venous extracorporeal membrane oxygenation     in-hospital mortality     high-volume centers     quality control     intensive care unit capacity parameters    

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Prevalence and determinations of physical inactivity among public hospital employees in Shanghai, China

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《医学前沿（英文）》 2015年 第9卷 第1期   页码 100-107 doi: 10.1007/s11684-014-0372-9

摘要：

This study aims to explore the prevalence and determinations of physical inactivity among hospital employees in Shanghai, China. A cross-sectional study of 4612 employees aged 19 to 68 years was conducted through stratified cluster sampling from different classes of Shanghai hospitals in 2011. The total physical activity was evaluated using the metabolic equivalent according to the Global Physical Activity Questionnaire. Among the participants, 38.5%, 32.3%, and 64.6% of the employees are inactive at work, commuting, and taking leisure time, respectively. Up to 41.8% of the men and 37.8% of the women (P = 0.012) are physically inactive. When the age and educational level are adjusted, male doctors and medical technicians show a higher percentage of physical inactivity than male workers in logistics (P = 0.001). Among females, employees who are working in second- and third-class hospitals show a higher proportion of physical inactivity than those who are working in community health care centers. Logistic regression analyses show that the odds ratios (ORs) of leisure-time physical inactivity associated with the intensity of physical activity at work are 2.259, 2.897, and 4.266 for men (P<0.001) and 2.456, 3.259, and 3.587 for women (P<0.001), respectively. The time during commuting activities is significantly associated with leisure-time physical inactivity in either sex (OR= 2.116 for men and 2.173 for women, P<0.001). Hospital employees, particularly doctors and medical technicians, show a higher proportion of physical inactivity than other inhabitants in Shanghai. The time and intensity of activity at work and commuting are associated with leisure-time activities.

关键词： prevalence     determination     employee     public hospital     cross-sectional study     physical inactivity    

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Investigating the impact of air pollution on AMI and COPD hospital admissions in the coastal city of

《环境科学与工程前沿（英文）》 2022年 第16卷 第5期 doi: 10.1007/s11783-021-1490-7

摘要：

• The impact of air pollution on AMI/COPD hospital admissions were examined.

关键词： AMI     COPD     Air pollution exposure     GAM    

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Assessment of leaching behavior and human bioaccessibility of rare earth elements in typical hospital

Chunfeng Wang, Guanfei Chen, Yanchen Zhu, Dan Yao, Wanfeng Wang, Lianjun Wang

《环境科学与工程前沿（英文）》 2017年 第11卷 第6期 doi: 10.1007/s11783-017-0946-2

摘要： Leaching behavior and gastrointestinal bioaccessibility of rare earth elements (REEs) from hospital waste incineration (HWI) fly and bottom ash samples collected from Beijing and Nanjing Cities were assessed. In the same ash sample, the leaching concentrations of individual REEs determined by the Toxicity Characteristic Leaching Procedure (TCLP) were higher than those detected by the European standard protocol (EN-type test), thereby suggesting that the low pH value of leaching solution was an important factor influencing the leachability of REE. The REE bioaccessibility results, which were evaluated using the physiologically based extraction test (PBET), indicated that REEs were highly absorbed during gastric phase by dissolution; and subsequently precipitated and/or re-adsorbed in small intestinal phase. The relative amounts of the total REEs extracted by the TCLP method, EN-type test and PBET test were compared. In addition to the pH value of extraction solutions, the chelating role of REEs with organic ligands used in the PBET method was also an important parameter affecting REE adsorption in human body. Additionally, this study showed that REEs were extracted by these methods as concomitants of heavy metals and anions (NO , F , SO , and Cl ) from HWI ash, which probably caused the remarkably complex toxicity on human body by the exposure pathway.

关键词： Assessment     Rare earth elements     Leaching behavior     Bioaccessibility     Hospital waste    

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follow-up after colorectal adenoma polypectomy is important: A multiple-center study in symptomatic hospital-based

Qin-Yan GAO, Hui-Min CHEN, Jing-Yuan FANG, Jian-Qiu SHENG, Ping ZHENG, Cheng-Gong YU, Bo JIANG,

《医学前沿（英文）》 2010年 第4卷 第4期   页码 436-442 doi: 10.1007/s11684-010-0200-9

摘要： The recurrence of colorectal adenoma (CRA) is high. Although there are guidelines for colonoscopy surveillance after polypectomy in other countries, little is known about its recurrence rate and recurrence peak, especially in China. The aim of the present research is to investigate how long after polypectomy follow-up should take and to analyze risk factors of recurrence. 1208 patients who received polypectomies from five clinical research centers in four regions of China (Shanghai, Guangzhou, Nanjing and Beijing) were included. They were divided into 4 groups: group A (follow-up≤1 year after polypectomy), group B (follow-up 2–3 years after polypectomy), group C (follow-up 4–5 years after polypectomy), and group D (follow-up>5 years after polypectomy). The sex, age, adenoma location, size, number, and pathological characteristics were compared. On the whole, the recurrence rate was 59.46% in group A, 61.09% in group B, 78.07% in group C, and 87.12% in group D, which indicated an increased tendency with a prolonged follow-up duration. There was a significant difference between group A and C or D, and between group B and C or D (<0.01), but there was no statistical difference between group A and B. Additionally, the recurrent patients in the first year had a recurrence rate of 97.33% in the first three years (59.46/61.09), which means that the peak of recurrence was almost entirely concentrated in the first year. The recurrence rate was higher in males and the elder. The risk factors included multiple numbers, villous feature, high-grade dysplasia of medium or smaller size and location in the distal colon. In conclusion, the peak of recurrence was almost totally concentrated in the first year; meanwhile, the first year follow-up is of critical importance in China. It may not be necessary to do the follow-up examination during the second and third years, but after three years, another colonoscopy should be undertaken.

关键词： colorectal adenoma     polypectomy     follow-up     recurrence     risk factor    

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Occurrence and migration of microplastics and plasticizers in different wastewater and sludge treatmentunits in municipal wastewater treatment plant

《环境科学与工程前沿（英文）》 2022年 第16卷 第11期 doi: 10.1007/s11783-022-1577-9

摘要：

● Reduce the quantifying MPs time by using Nile red staining.

关键词： Microplastics     Municipal wastewater treatment plant     Phthalate esters     Thermal hydrolysis    

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activity of topical agents against Propionibacterium acnes: an in vitro study of clinical isolates from a hospital

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《医学前沿（英文）》 2016年 第10卷 第4期   页码 517-521 doi: 10.1007/s11684-016-0480-9

摘要：

This study aimed to compare the antimicrobial activities of topical agents against Propionibacterium acnes isolated from patients admitted to a hospital in Shanghai, China. The minimal inhibitory concentrations of the cultured P. acnes were determined in accordance with the Clinical and Laboratory Standards Institute. Susceptibilities to clindamycin and erythromycin were compared in terms of gender, age, disease duration, previous treatment, and disease severity. A total of 69 P. acnes strains were isolated from 98 patients (70.41%). The susceptibility to triple antibiotic ointment (neomycin/bacitracin/polymyxin B) and bacitracin was 100%. The susceptibility to fusidic acid was 92.7%. The resistance rates to neomycin sulfate, erythromycin, and clindamycin were 11.7%, 49.3%, and 33.4%, respectively. The high resistance rate to clindamycin and erythromycin was significantly affected by gender, previous treatment, and disease severity rather than by age and disease duration. Topical antibiotics should not be used separately for long-term therapy to avoid multiresistance. The use of topical antibiotics should be determined by clinicians on the basis of clinical conditions.

关键词： antimicrobial susceptibility/resistance     Propionibacterium acnes     topical antibiotics     in vitro study    

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Microplastics in municipal wastewater treatment plants: a case study of Denizli/Turkey

《环境科学与工程前沿（英文）》 2023年 第17卷 第8期 doi: 10.1007/s11783-023-1699-8

摘要：

● High amounts of microplastics are released to receiving media from WWTPs.

关键词： Microplastics     Wastewater treatment plant     Removal efficiency     Daily discharge    

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China Launched the First Wastewater Resource Recovery Factory in Yixing

《环境科学与工程前沿（英文）》 2022年 第16卷 第1期 doi: 10.1007/s11783-021-1496-1

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Inhibition character of crotonaldehyde manufacture wastewater on biological acidification

《环境科学与工程前沿（英文）》 2021年 第15卷 第6期 doi: 10.1007/s11783-021-1403-9

摘要：

• The inhibition of the main organic pollutions in CMW was demonstrated.

关键词： Crotonaldehyde manufacture wastewater     Biological acidification     Volatile fatty acids     Inhibition     Toxic units    

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“NEW” resource recovery from wastewater using bioelectrochemical systems: Moving forward with functions

Akshay Jain, Zhen He

《环境科学与工程前沿（英文）》 2018年 第12卷 第4期 doi: 10.1007/s11783-018-1052-9

摘要：

Resource recovery from wastewater is a key function of bioelectrochemical systems.

NEW resources to recover include Nutrient, Energy, and Water.

Identifying proper application niches can guide BES research and development.

More efforts should be invested to the application of recovered resources.

A mindset for energy performance and system scaling is critically important.

关键词： Bioelectrochemical systems     Resource recovery     Wastewater treatment     Energy     Nutrients    

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标题 作者 时间 类型 操作

Membrane bioreactors for hospital wastewater treatment: recent advancements in membranes and processes

期刊论文

Removal efficiencies of natural and synthetic progesterones in hospital wastewater treated by different

期刊论文

Qualitative analysis of direction of public hospital reforms in China

null

期刊论文

SinoSCORE: a logistically derived additive prediction model for post-coronary artery bypass grafting in-hospital

null

期刊论文

Association between ICU quality and in-hospital mortality of V-V ECMO-supported patients—the ECMO quality

期刊论文

Prevalence and determinations of physical inactivity among public hospital employees in Shanghai, China

null

期刊论文

Investigating the impact of air pollution on AMI and COPD hospital admissions in the coastal city of

期刊论文

Assessment of leaching behavior and human bioaccessibility of rare earth elements in typical hospital

Chunfeng Wang, Guanfei Chen, Yanchen Zhu, Dan Yao, Wanfeng Wang, Lianjun Wang

期刊论文

follow-up after colorectal adenoma polypectomy is important: A multiple-center study in symptomatic hospital-based

Qin-Yan GAO, Hui-Min CHEN, Jing-Yuan FANG, Jian-Qiu SHENG, Ping ZHENG, Cheng-Gong YU, Bo JIANG,

期刊论文

Occurrence and migration of microplastics and plasticizers in different wastewater and sludge treatmentunits in municipal wastewater treatment plant

期刊论文

activity of topical agents against Propionibacterium acnes: an in vitro study of clinical isolates from a hospital

null

期刊论文

Microplastics in municipal wastewater treatment plants: a case study of Denizli/Turkey

期刊论文

China Launched the First Wastewater Resource Recovery Factory in Yixing

期刊论文

Inhibition character of crotonaldehyde manufacture wastewater on biological acidification

期刊论文

“NEW” resource recovery from wastewater using bioelectrochemical systems: Moving forward with functions

Akshay Jain, Zhen He

期刊论文